From: Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A2
Compound injected | Number of mast cells (× 103) | |
---|---|---|
Saline |  | 14.6 (6.1 – 23) |
TM-N49 |  | 49.3 (20.3 – 65.9) |
L-selectin Ab | + TM-N49 | 38.0 (19.1 – 68.8) |
LFA-1 Ab | + TM-N49 | 33.7 (18.9 – 55.2) * |
CD18 Ab | + TM-N49 | 25.1 (10.4 – 39.8)* |
ICAM-1 Ab | + TM-N49 | 14.8 (9.6 – 32.0)* |
Hamster IgG1 | + TM-N49 | 39.8 (17.0 – 63.1) |
Rat IgG2a | + TM-N49 | 43.3 (19.3 – 58.0) |