Figure 1

CAPE inhibited IL-12 p40, IL-12 p70, IL-10 and IP-10 production in human MoDCs. Immature MoDCs (10⁶ cells/mL) were cultured for 48 hours either in the absence or presence of CAPE (10 μM) under LPS (100 ng/mL) or crude mite extract (100 μg/mL) stimulation. Cytokine levels in the supernatant from ten non-atopic healthy subjects and six mite-sensitized allergic patients were measured by ELISA according to the manufacturer's instructions. *P < 0.05; **P < 0.01.