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Figure 1 | BMC Immunology

Figure 1

From: Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining

Figure 1

Mtb PPD-specific cytokine/chemokine biomarker responses 1 month post BCG vaccination of UK adolescents. Plots representing concentrations of indicated biomarkers (see y-axis legends) are shown as measured by multiplex bead array assay on supernatants from 6 day diluted whole blood assays. Blood samples were donated from individuals (n = 12) prior to or 1 month following BCG vaccination. The dotted line indicates the lower limit of detection of the assay (3.2 pg/ml) and each data point represents the concentration measured in PPD-stimulated sample minus that measured in unstimulated sample. The Wilcoxon Signed Rank test was used to calculate p-values between pre and post-vaccination sample groups.

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BMC Immunology

ISSN: 1471-2172

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