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Table 2 The medians of parameters and statistic data in the three groups

From: The balance between intrahepatic IL-17+ T cells and Foxp3+ regulatory T cells plays an important role in HBV-related end-stage liver disease

    

P value

Group(N)

ACLF(31)a

CLF(26)a

NC(12)a

ACLF vs CLF

ACLF vs NC

CLF vs NC

IL-17(%)

3.18(2.31)

1.90(0.84)

0(1.41)

.000

.000

.000

FoxP3 (%)

0.36(0.55)

0.23(0.44)

0.00(1.42)

.621

.000

.000

IL17/Foxp3

7.00(10.30)

4.33(4.66)

0.00(1.5)

.004

.000

.002

CD4 (%)

60.94(8.77)

57.24(15.06)

45.84(16.22)

.060

.000

.000

IL-17/CD4(%)

5.32(4.51)

3.49(2.11)

0(4.92)

.008

.001

.019

FoxP3/CD4(%)

0.62(0.93)

0.69(1.06)

1.35(5.11)

.215

.937

.577

CD8 (%)

35.90(8.82)

38.71(14.91)

46.38(15.47)

.054

.000

.000

Perforin (%)

7.50(4.35)

5.16(3.32)

2.03(4.17)

.086

.002

.003

  1. The proportion of positively stained cells on the liver inflammatory cells in five randomly-selected high power fields (hpf, ×400) were analyzed by two independent observers who were blinded to the clinical data of the liver tissues.
  2. a The frequency and ratio of positive cells in the three groups are expressed as medians (interquartile range).
  3. NC, normal control; CLF, HBV-related chronic liver failure; ACLF, HBV-related acute on chronic liver failure.
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BMC Immunology

ISSN: 1471-2172

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