Figure 5
From: Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection
Liver infiltration of CD39+ Treg cells in hepatitis B patients. (A) LILs from distal liver tissue of patients with liver hemangioma and HBV infection (HAI: S3/G3) were stained with anti-CD4, -CD45RA, -FoxP3, or -CD39 mAbs and analyzed by FCM assays. (B) Diagnostic needle-biopsy liver samples of CHB patients were stained with anti-CD39 or -FoxP3 mAb. # denotes the same region of adjacent sections. (C) Co-localization of CD4, CD39, and FoxP3 expressions are shown by immunofluorescence in diagnostic needle-biopsy liver samples of CHB patients. (D) Numbers of CD39+FoxP3- /CD39-FoxP3+ /CD39+FoxP3+ cells in liver portal areas are shown in CAH patients. Each dot represents one individual. Horizontal bars represent the median positive numbers.