Cell line | LaDR5 (%) | standard DR5-mAb (%) |
---|
Jurkat | 57.05 | 79.12 |
K562 | 0.4 | 10.92 |
Daudi | 63.78 | 95.45 |
U937 | 86.07 | 98.18 |
- LaDR5 could bind the membrane DR5 on Jurkat (the percentage of positive cells was 57.05 %), Daudi (63.78 %) and U937 (86.07 %), which was essentially consistent with the standard anti-DR5 antibody treated samples (79.12 % in Jurkat, 95.45 % in Daudi and 98.18 % in U937). In K562 cells, the percentage of positive cells in standard anti-DR5 antibody treated sample was 10.92 % contrasting to 0.4 % in LaDR5 incubated sample.