Figure 6

CD72Δex8 augments and ER stress-induced apoptosis in the mouse B cell line WEHI-231 and human B cell line Raji. A and B: Enhancement of apoptosis by CD72Δex8 in WEHI-231 (A) and Raji (B). C: cells were stimulated with staurosporine. Apoptotic cells containing hypodiploid DNA were analyzed by flow cytometry using a FACSCalibur. Values are the mean ± SD of triplicate determinations. *P < 0.01, **P < 0.001, ***P < 0.0001 (Student’s t-test). Representative data from three experiments are shown.