Gene | Different genetics models | Â | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
IL1A | Â | Controls | Cases | Multiplicative | Additive | Dominant | Recessive | ||||
SNP ID | Genotype | No (%) | No (%) | P value | OR | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) |
RS1304037 | AA | 161 (83.9) | 130 (77.8) | 0.262 | 1.32 (0.81-2.15) | Â | Â | 0.147 | 1.48 (0.87-2.51) | 0.386 | 0.38 (0.04-3.69) |
AG | 28 (14.6) | 36 (21.6) | Â | Â | 0.223 | 0.26 (0.03-2.63) | Â | Â | Â | Â | |
GG | 3 (1.5) | 1 (0.6) | Â | Â | 0.432 | 0.41 (0.04-4.02) | Â | Â | Â | Â | |
rs16347 | DEL/DEL | 81 (42.2) | 68 (40.7) | 0.482 | 1.12 (0.82-1.51) | Â | Â | 0.778 | 1.06 (0.70-1.62) | 0.323 | 1.36 (0.74-2.48) |
DEL/TGAA | 88 (45.8) | 73 (43.7) | Â | Â | 0.343 | 1.36 (0.72-2.59) | Â | Â | Â | Â | |
TGAA/TGAA | 23 (12.0) | 26 (15.6) | Â | Â | 0.367 | 1.35 (0.70-2.57) | Â | Â | Â | Â | |
rs17561 | GG | 166 (86.5) | 121 (72.5) | 0.003 | 2.08 (1.27-3.41) | Â | Â | 0.001 | 2.43 (1.42-4.15) | 0.646 | 0.54 (0.05-6.37) |
GT | 24 (12.5) | 45 (26.9) | Â | Â | 0.260 | 0.27 (0.02-3.10) | Â | Â | Â | Â | |
TT | 2 (1.0) | 1 (0.6) | Â | Â | 0.758 | 0.69 (0.06-7.66) | Â | Â | Â | Â | |
rs2071373 | CC | 80 (41.7) | 68 (40.7) | 0.443 | 1.13 (0.83-1.53) | Â | Â | 0.856 | 1.04 (0.68-1.59) | 0.194 | 1.51 (0.81-2.84) |
CT | 92 (47.9) | 74 (44.3) | Â | Â | 0.191 | 1.55 (0.80-3.02) | Â | Â | Â | Â | |
TT | 20 (10.4) | 25 (15.0) | Â | Â | 0.259 | 1.47 (0.75-2.88) | Â | Â | Â | Â |