Table 3 Inter-species cross-reactivity of anti-CD38 mAbs
From: Characterization and phylogenetic epitope mapping of CD38 ADPR cyclase in the cynomolgus macaque
| Â | Macaque CD38 | Human CD38 | ||
|---|---|---|---|---|
MAbs | native | DTT | native | DTT |
Anti-macaque CD38 | ||||
   KK1B5 | + | - | + | - |
   KK4E5 | + | + | - | - |
   KK6A11 | + | + | - | - |
   KK9H4 | + | - | + | - |
Anti-human CD38 | ||||
   IB4 | - | - | + | + |
   IB6 | - | - | + | + |
   HB7 | - | - | + | + |
   AT1 | + | - | + | - |
   OKT10 | + | - | + | - |
   SUN-4B7 | + | - | + | - |