Open Access

Erratum to: Characterisation of RT1-E2, a multigenic family of highly conserved rat non-classical MHC class I molecules initially identified in cells from immunoprivileged sites

  • Pierre Lau1,
  • Claire Amadou1,
  • Hélène Brun1,
  • Virginie Rouillon1,
  • Fiona McLaren2,
  • Anne-France Le Rolle2,
  • Margaret Graham2,
  • Geoffrey W Butcher2 and
  • Etienne Joly1, 2Email author
BMC Immunology20045:4

DOI: 10.1186/1471-2172-5-4

Received: 10 February 2004

Accepted: 19 February 2004

Published: 19 February 2004

The original article was published in BMC Immunology 2003 4:7

In this article, [1] figure 2 was generated using the pretty output of the GCG software suite. Residues in agreement with the consensus appear as -, whilst gaps are shown as dots.

Because of inaccurate settings in the software when generating the figure originally published, however, Y vs F and W vs R differences between individual sequences and the consensus were ignored, and therefore appeared as -. Such errors occurred at 9 different positions (14, 21, 22, 46, 55, 74 107, 116, 302) of the alignment, and are corrected here.

These mistakes only concerned this figure, and had no influence on the trees shown on Fig. 3 or on any of the other results and conclusions of this paper.
Figure 1

Alignment of RT1-E2 protein sequences deduced from the cDNA sequences summarised in Table 1 with those of other rat class I sequences. For E2ba (acc. AJ537439), the translated sequence ends prematurely because of a frameshift at the start of exon 5 (see text). The line E2ba* shows the notional downstream translation of the cDNA sequence if this frameshift was not present. In the sequences from which the RT1-E2g (acc. AJ243338) sequence was compiled (p57, p4.4, p4.6), underlined residues correspond to positions that differ from all the other RT1-E2 sequences, and could therefore be due to either PCR mutations or true allelic differences. Others accession numbers are as follows: E2bu: AJ537420, E2bl: AJ537417, E2an (deduced from genomic): AJ315490, E2al: AJ276126, E2cl: AJ537418, E2dl: AJ537419, E2dc: AJ537441, Eav1: AJ537440, Eu: AJ306619, Al: L26224, Aa: M31018, Au: X82106. Alignment of the corresponding DNA sequences is available as supplementary data or upon request atn@cict.fr.

Notes

Declarations

Authors’ Affiliations

(1)
IFR Claude de Préval, INSERM U563
(2)
The Functional Immunogenetics Laboratory, The Babraham Institute

References

  1. Lau P, Amadou C, Brun H, Rouillon V, McLaren F, Le Rolle AF, Graham M, Butcher GW, Joly E: Characterisation of RT1-E2, a multigenic family of highly conserved rat non-classical MHC class I molecules initially identified in cells from immunoprivileged sites. BMC Immunol. 2003, 4: 7-10.1186/1471-2172-4-7.PubMed CentralView ArticlePubMedGoogle Scholar

Copyright

© Lau et al; licensee BioMed Central Ltd. 2004

This article is published under license to BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

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