Figure 3
From: The allergy adjuvant effect of particles – genetic factors influence antibody and cytokine responses
The primary cellular response in the draining lymph node The primary cellular response in the draining PLN was determined five days after a single injection of HBSS (open columns), 10 μg OVA (gray), 40 μg PSP (hatched) or 10 μg OVA + 40 μg PSP (black) into both hind footpads of BALB/cA, NIH and C3H/HeN mice. The total lymph node cell numbers (A) and IL-4 (B), IFN-γ (C) and IL-10 (D) secreted from the PLN cells after ex vivo stimulation with Con A were determined. Values for individual samples (circles) and group median values (columns) are shown. Dotted lines indicate the lower detection limits for the cytokine ELISA assays, and brackets indicate statistically significant differences between groups (p < 0.05).