Figure 3

Reduced T cell expansion in response to SEB exposure in vivo. a) WT (filled circles) or ITK deficient mice (open circles) were injected with 50 μg SEB i.p. and peripheral blood lymphocytes analyzed after 2, 4 and 5 days as in the materials and methods for the percentage of Vβ8⁺CD4⁺ T cells as indicated (Vβ6⁺CD4⁺ T cells showed no change, data not shown). b) The same data plotted as fold increase in percentage of Vβ8⁺CD4⁺ T cells in peripheral blood. * indicates a statistically significant difference with a p < 0.05.