Figure 2From: BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1BMP-6 induces cell death in B cells. CD19+CD27- naïve B cells or CD19+CD27+ memory B cells were cultured for 48 h with BMP-6 (1 μg/ml) with or without anti-IgM (37.5 μg/ml). Cell death (PI+ cells) was then measured by flow cytometry analysis. Data are shown as mean percentage PI+ cells from five independent donors (± SEM; p ≤ 0,003).Back to article page