Control (N = 10) | HIV (n = 21) | P-value | |
---|---|---|---|
Leg tissue volume (values in cm3) a | |||
Total circumference | 651 (170) | 637 (170) | 0.841 |
Muscle tissue | 353 (69.6) | 336 (52.8) | 0.483 |
Subcutaneous adipose tissue | 185 (105) | 155 (116) | 0.512 |
Inter-muscular adipose tissue | 97.2 (25.8) | 102 (26.2) | 0.601 |
Leg tissue percent of total circumference a | |||
Muscle tissue | 54.8 (4.2) | 54.3 (8.8) | 0.875 |
Subcutaneous adipose tissue | 28.0 (14.3) | 22.6 (10.0) | 0.259 |
Inter-muscular adipose tissue | 15.1 (2.7) | 16.4 (3.3) | 0.315 |
Thigh muscle strength & fatigue | |||
Knee extension peak torque (Nm) | 96.4 (40.1) | 103.9 (30.4) | 0.562 |
Knee flexion peak torque (Nm) | 50.7 (22.3) | 53.7 (20.0) | 0.705 |
Knee extension total work (joules) | 3039 (1453) | 3396 (967) | 0.422 |
Knee flexion total work (joules) | 1552 (800) | 1561 (744) | 0.977 |
Knee extension fatigue index (joules) | −704 (600) | −781 (581) | 0.735 |
Knee flexion fatigue index (joules) | −288 (355) | −322 (294) | 0.784 |
SPPB | |||
4-meter gait speed (m/sec) | 1.11 (0.10) | 1.0 (0.18) | 0.102 |
4-meter gait speed score (range: 0–4) | 4 (0) | 3.8 (0.51) | 0.253 |
Time to complete 5 chair stands (sec) | 10.2 (2.1) | 12.1 (2.4) | 0.047 |
Chair stand score (range: 0–4) | 3.6 (0.51) | 3.0 (0.97) | 0.105 |
Balance score (range: 0–4) | 4 (0) | 3.85 (0.65) | 0.499 |
Total performance score (range: 0–12) | 11.6 (0.51) | 10.7 (1.9) | 0.167 |
400-meter rapid walk | |||
400-meter rapid gait speed (m/sec) | 1.42 (0.16) | 1.28 (0.24) | 0.126 |
Average exertion (range: 0–10) | 1.47 (1.70) | 1.14 (1.04) | 0.585 |
Maximal exertion (range: 0–10) | 2.69 (2.89) | 2.03 (1.52) | 0.502 |
Lap variability in gait speed (m/sec) | 2.07 (4.21) | 1.08 (0.48) | 0.465 |