Illness progression in chronic fatigue syndrome: a shifting immune baseline

BMC Immunology

Table 1 Extrapolation of classification models identified in adolescent CFS (Broderick et al., 2012) to adult pre and post-menopausal groups

Classification based on	Stepwise model of IL-1α, 6,8,13,23	Consensus model of IL-6, 8, and 23	Minimal model of IL-6 and 8
(a) Training set: Age < =18 years
Correct rate	0.93	0.86	0.79
Error rate	0.07	0.14	0.21
Sensitivity	0.94	0.89	0.78
Specificity	0.92	0.83	0.79
Positive predictive value	0.89	0.80	0.74
Negative predictive value	0.96	0.91	0.83
(b) Test set: 18 < Age < = 50 years
Correct rate	0.49	0.26	0.35
Error rate	0.51	0.74	0.65
Sensitivity	0.09	0.23	0.09
Specificity	0.90	0.29	0.62
Positive predictive value	0.50	0.25	0.20
Negative predictive value	0.49	0.26	0.39
(c) Test set: Age > 50 years ^a
Correct rate	0.46	0.29	0.39
Error rate	0.54	0.71	0.61
Sensitivity	0.00	0.32	0.14
Specificity	0.93	0.25	0.64
Positive predictive value	0.00	0.30	0.29
Negative predictive value	0.48	0.27	0.43

ISSN: 1471-2172