Fig. 2

C. albicans is not cleared completely from lungs of cPLA₂α^−/− mice and disseminates to the kidney. cPLA₂α^−/− (open circles) and cPLA₂α^+/+ (closed circles) mice were challenged with either 10⁶ or 10⁷ C. albicans (CA), and CFU were determined at the indicated times in homogenized (a) lung and (b) kidney (n = 3–14 mice/group, from 3–6 independent experiments). *P < 0.05 compared to cPLA₂α^+/+