Fig. 3
From: Immune modulation of CD4+CD25+ regulatory T cells by zoledronic acid
ZA influences the expression of markers associated with Treg cells suppressive function. Representative flow cytometry results of (a) CCR4 and (b) CTLA4 on Treg cells treated with 100 μM ZA (dotted line) and untreated Treg cells (shaded histogram). The negative control (unstained Treg cells) is shown as an open histogram. Median fluorescence intensity (MFI) is plotted against the ZA concentration (μM); the results from four independent experiments are shown. Significant difference in MFI determined using the one-way ANOZA;*p < 0.05