Fig. 1
From: Hybrid approach to model the spatial regulation of T cell responses
Schematic representation of the model. Naive T cells and antigen presenting cells (APC) enter the lymph node. Due to asymmetric cell division, some T cells differentiate. Mature CD8 + T cells leave the lymph node and kill infected cells. Mature CD4 + T cells produce IL-2 that influences cell survival and differentiation. APCs are shown in green, naive T cells are white. Differentiated CD4 + T cells are yellow and CD8 + T cells are blue. Levels of yellow and blue indicate cell maturation