Table 3 Two years OS based on donor KIR and recipient HLA relationship
Comparison groups | Patient number | Median OS (%) | HR | P value |
|---|---|---|---|---|
KIR/HLA mismatch vs. KIR/HLA match | 30 vs. 24 | 87.5 vs. 61.9 | 2.92 |  < 0.04 |
KIR B/x haplotype with 2DS2 vs. KIR A/A haplotype | 20 vs. 17 | 88 vs. 79.1 | 0.34 | 0 .05 |
KIR B/x haplotype w/o 2DS2 vs. KIR A/A haplotype | 17 vs. 17 | 57.3 vs. 79.1 | 0.63 | 0.01 |
KIR B/x haplotype with 2DS2 vs. KIR B/x w/o 2DS2 | 20 vs. 17 | 88 vs. 57.3 | 0.42 | 0.006 |
KIR B/x haplotype with 2DS1 vs. KIR A/A haplotype | 24 vs. 17 | 94 vs. 79.1 | 0.63 | 0.05 |
KIR B/x haplotype w/o 2DS1 vs. KIR A/A haplotype | 13 vs. 17 | 76.1 vs. 79.1 | 1.63 | ns |
KIR B/x haplotype with 2DS1 vs. KIR B/x w/o 2DS1 | 24 vs. 13 | 94 vs. 76.1 | 0.42 | 0.001 |
Activating KIR/HLA mismatch vs. KIR/HLA match | 8 vs 24 | 94 vs 61.9 | 0.46 | 0.03 |
Inhibitory KIR/HLA mismatch vs. KIR/HLA match | 22 vs 24 | 81 vs 61.9 | 0.93 | 0.06 |