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Table 2 Association between plasma cytokine/chemokine expression with lung cavitation among HIV positive and negative participants with DR-TB (n = 125)

From: Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis

Cytokine/

Chemokine

Univariable

 

Multivariable

RR

95% CI

p-value

 

aRR

95% CI

p-value

IL-1Ra

1.158

0.761–1.760

0.494

 

1.115

0.736–1.689

0.607

IL-4

0.941

0.620–1.426

0.773

 

1.127

0.742–1.713

0.575

IL-6

1.347

1.006–1.803

0.045

 

1.405

1.079–1.829

0.011

IL-7

0.871

0.713–1.064

0.176

 

0.922

0.756–1.125

0.425

IL-8

1.019

0.557–1.863

0.951

 

0.967

0.583–1.603

0.896

IL-9

1.025

0.535–1.964

0.940

 

1.112

0.601–2.059

0.735

IL-13

0.853

0.628–1.157

0.307

 

0.851

0.624–1.161

0.309

G-CSF

0.967

0.821–1.139

0.689

 

0.987

0.850–1.147

0.868

MCP-1

0.951

0.749–1.208

0.682

 

1.072

0.828–1.387

0.597

FGF

1.393

0.659–2.944

0.386

 

1.324

0.614–2.859

0.474

MIP-1α

1.183

0.959–1.458

0.116

 

1.139

0.924–1.403

0.222

MIP-1β

1.084

0.530–2.218

0.825

 

1.199

0.609–2.361

0.600

TNF-α

0.934

0.635–1.375

0.731

 

1.097

0.766–1.572

0.614

PGDF-BB

1.075

0.802–1.441

0.628

 

1.175

0.891–1.550

0.253

Eotaxin

1.044

0.688–1.586

0.839

 

1.206

0.795–1.832

0.378

IP-10

1.039

0.797–1.354

0.778

 

1.116

0.880–1.414

0.366

GM-CSF

0.926

0.574–1.492

0.752

 

0.902

0.591–1.376

0.631

IFN-γ

0.751

0.502–1.124

0.164

 

0.808

0.552–1.185

0.275

IL-10

1.177

0.796–1.740

0.414

 

1.131

0.761–1.681

0.544

IL-12

0.868

0.607–1.241

0.438

 

0.887

0.627–1.256

0.499

IL-17

1.115

0.779–1.596

0.553

 

1.108

0.788–1.557

0.556

IL-1b

1.045

0.730–1.498

0.809

 

0.958

0.678–1.354

0.809

VEGF

1.155

0.741–1.801

0.525

 

1.176

0.792–1.744

0.378

RANTES

0.767

0.542–1.085

0.134

 

0.853

0.608–1.198

0.359

  1. *Three participants were excluded due to missing lung cavitation status