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Fig. 2 | BMC Immunology

Fig. 2

From: Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies

Fig. 2

IIM patients exhibit a lower CD3 TN cell population and a higher CD3 TEMRA cell population in the pheripheral blood. Flow cytometry analyses of surface markers CD3, CD62L and CD45RA surface markers in PBMCs of IIM patients with anti-aminoacyl-tRNA synthetase (ARS + , n = 40), or with anti-MDA5 antibody (MDA5 + , n = 24), and healthy controls (HC, n = 60). A A representative data was shown. Naïve T (TN, CD45RA + CD62L +), central memory T (TCM, CD45RA-CD62L +), effector memory T (TEM, CD45RA-CD62L-), and terminally differentiated effector memory T cells (TEMRA, CD45R + CD62L-) (B) Each dot was displayed for each data from the enrolled subjects. Data are presented as means ± SD. The p values were calculated using Kruskal–Wallis test between ARS + , MDA5 + , and HC groups. ns, not significant

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BMC Immunology

ISSN: 1471-2172

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