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Fig. 4 | BMC Immunology

Fig. 4

From: Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies

Fig. 4

IIM patients with anti-MDA5 autoantibody have a higher Treg cell population in the pheripheral blood. Flow cytometry analyses of CD3, CD4, and Foxp3 markers in PBMCs of IIM patients with anti-aminoacyl-tRNA synthetase (ARS + , n = 40), or with anti-MDA5 antibody (MDA5 + , n = 22), and healthy controls (HC, n = 60). A A representative data was shown. Treg cells were defined as CD3 + CD4 + Foxp3 + . B Each dot was displayed for each data from the enrolled subjects. Data are presented as means ± SD. The p values were calculated using Mann–Whitney U test between the MDA5 and ARS groups, or using Kruskal–Wallis test between the MDA5, ARS, and HC groups

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