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Fig. 4 | BMC Immunology

Fig. 4

From: Bcl-3 regulates T cell function through energy metabolism

Fig. 4

Bcl-3 deficiency inhibits ROS production and promote the necrosis and IFN-γ production of cells with stimulated by CD3/CD28. Jurkat and Bcl-3−/− Jurkat cells were activated with anti-CD3/CD28 for 24 h. (A) The intracellular ROS levels were stained using the ROS assay kit and determined by flow cytometry. (B) Cell apoptosis (B) and IFN-γ production (C)were determined by flow cytometry

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