Fig. 6

MENK upregulated CD8⁺ T_EM cells and CD4⁺/CD8⁺ T_CM cells of mice infected with influenza virus. A Representative dot plots of CD4⁺T_EM cells (CD4⁺CD44^hiCD62L^lo) and T_CM cells (CD4⁺CD44^hiCD62L^hi) in BALF, lung, and LN of mice on day 10 p.i. B Representative dot plots of CD8⁺ T_EM cells (CD8⁺CD44^hiCD62L^lo) and T_CM cells (CD8⁺CD44^hi CD62L^hi) in BALF, lung, and LN of mice on day 10 p.i. C Panel presenting the proportions of CD4⁺/CD8⁺ T_EM cells and T_CM cells. The data represent the mean ± SD of three independent experiments (each performed with n = 6 mice). ^★p < 0.05, ^★★p < 0.01 versus the PR8 group