Table 1 Baseline Clinical Characteristics of the three studied groups

Age(years)

42.55 ± 8.84

(26 ~ 58)

40.76 ± 10.82

(22 ~ 58)

40.80 ± 9.81

(25 ~ 55)

0.558

Gender(M:F)

27:29

23:26

27:23

0.686

BMI(kg/m2)

21.69 ± 2.45

22.06 ± 1.85

21.59 ± 1.97

0.507

Virus strain

Respiratory syncytial virus

/

21

/

/

Human rhinovirus

/

11

/

/

Influenza

/

4

/

/

adenovirus

/

5

/

/

Parainfluenza virus

/

8

/

/

IgE (IU/mL)

85.49(23 ~ 465)^a

89.04(21 ~ 420)^a

58.79(22 ~ 223)

0.001

Atopy (yes/no)

21/35 ^a

19/30 ^a

7/43

0.009

FeNO (ppb)

37.83 ± 17.61 ^a

42.10 ± 17.36 ^a

21.84 ± 6.49

< 0.001

FEV1/predicted (%)

86.69 ± 12.73 ^a

79.94 ± 13.08 ^a

100.05 ± 10.84

< 0.001

FEV1/FVC (%)

83.48 ± 8.04^a

77.01 ± 10.72 ^a

89.37 ± 9.01

< 0.001

ACT scores

21.39 ± 2.02

19.00 ± 2.52 ^b

/

< 0.001

ACQ scores

1.18 ± 0.53

1.97 ± 0.74 ^b

/

< 0.001

Haematology

Leukocyte(10⁹/L)

6.43 ± 1.89

6.15 ± 1.81

5.89 ± 1.63

0.305

Eosinophil(%)

2.60 ± 1.11

3.02 ± 1.51

2.56 ± 1.38

0.163

Neutrophil (%)

57.31 ± 13.21

61.07 ± 12.96

56.35 ± 9.79

0.125

Eosinophil in induced sputum(%)

7.71(0.31 ~ 14.85) ^a

6.85(0.21 ~ 16.32) ^a

2.35(0 ~ 8.14)

< 0.001

Neutrophil in induced sputum(%)

64.78(43.68 ~ 93.32) ^a

65.33(40.69 ~ 91.25) ^a

47.18(15.52 ~ 76.95)

< 0.001