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Table 3 IHC stained lung tissue showing CD4 + T cell expression/unit area in various groups

From: Dominant negative biologics normalise the tumour necrosis factor (TNF-α) induced angiogenesis which exploits the Mycobacterium tuberculosis dissemination

Parameters

Different therapeutic groups of animals

M.tb infection 4th week

M.tb infection + Xpro-1595 treated 4th week

M.tb infection 8th week

M.tb infection + Xpro1595 treated 8th week

M.tb infection + DOTS

M.tb infection + DOTS + Xpro1595 treatment

Healthy

No. of cells/Unit area (mean)

214.31

175.8

162.52

176.73

139.28

103.43

77.83

P-Value

P**

No significance

P**