Fig. 3
Comparison of NK cells and clusters in non-improved patients before and after ALSS therapy. A Boxplots displaying the variation of immune cells in non-improved patients at the total immune cells level. B Pie charts displaying the frequency of immune cell subsets in the PBMC before and after ALSS therapy. C The frequency of C13 (CD56high NK cell) significantly reduced in non-improved patients after ALSS. D The expression of CD56 in 37 clusters. C13–16 were marked with red dotted box. p < 0.05 was considered statistically significant, *p < 0.05. **p < 0.01. NK: natural kill; ALSS: artificial liver support system; PBMC: peripheral blood mononuclear cells