Fig. 5

Evaluation of SARS-CoV-2 vaccination on humoral and cellular immunity. Analysis of a subset of 65 patients who received their first 2 vaccinations between two subsequent visits (Prior: A visit where the participant had not been vaccinated, Post: The subsequent visit, where the participant had received 2 vaccinations). a SARS-CoV-2 S-specific IgG levels (b) Percentage of SARS-CoV-2 S-specific CD4 + and CD8 + memory T cells analysed by ICS after stimulation with the S-small peptide pool. c Percentage of SARS-CoV-2 S-specific CD4 + and CD8 + T cells analysed by AIM after stimulation with the S-large pool. d IFNγ production by SARS-CoV-2 S-specific cells (S-large pool). Horizontal line shows median. Statistical comparisons were performed using Wilcoxon unpaired signed-ranks test adjusted using Bonferroni. *P ≤ 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001