Fig. 4

Analysis of LVD and Ne groups. A Box plot of the quantity of CDR3 sequences numbers. B The PCA plot for TCR profiles. C Diversity analysis of D50 diversity index. D Diversity analysis of Gini index. Groups were compared using unpaired Student 's t-test. E–F treemap of module CDR3 sequences abundances in LVD group (E) and Ne group (F). G-H Logo plots showed consensus CDR3 motifs in LVD group (G) and Ne group (B), which illustrated amino acid CDR3 sequences whose expressed abundances were in top 50. Yellow indicated the LVD group, purple indicated the Ne group