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Fig. 3 | BMC Immunology

Fig. 3

From: Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice

Fig. 3

Th1 responses are specific to the H. pylori antigen are selectively boosted by oral vaccination with Alginate/pCI-neo-UreH and Orally immunized mice with whole-cell killed H. pylori Hel 305 and other groups. Two weeks after the previous immunization cycle, cells were extracted from the spleen (A, C) and mesenteric lymph nodes (B, D). ELISA collected and analysed Supernatants for either IFN-γ (A, B) or IL-17 A (C, D). Data from three trials with n = 5 mice per group and experiment. **p < 0.01, *** < 0.001

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