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Fig. 1 | BMC Immunology

Fig. 1

From: Dendritic cells under allergic condition enhance the activation of pruritogen-responsive neurons via inducing itch receptors in a co-culture study

Fig. 1

TDI-induced chronic ACD mouse model. (A) Protocol for TDI-induced chronic ACD mouse model. (B) Ear swelling of TDI-sensitized group during the challenge phase of TDI-induced ACD. (C) Itch reaction during the challenge phase of TDI-induced ACD. Scratching bouts were monitored from day 28 to day 40. (D) Representative images of H&E staining of ear skin of control and TDI-sensitized group. Summary of epidermal (E) and dermal (F) thickness of ear skin. (G) Summary of the number of eosinophils per observation field. (H) The total serum IgE levels. Results are expressed as mean ± S.D. (N = 8 * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.01, Independent t-test vs. control group)

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