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Fig. 2 | BMC Immunology

Fig. 2

From: Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn’s disease correlates with disease activity

Fig. 2

Immune activation of intestinal CD8+ γδT cells in active CD patients was affected by the varying degrees of disease activity. (A) Pooled data compared the HLA-DR expression on CD8+ γδ T cells in the intestinal mucosa of HCs and active CD patients. (B) Pooled data compared the PD-1 expression on CD8+ γδ T cells in the intestinal mucosa of HCs and active CD patients. (C) Pooled data compared the HLA-DR expression on CD8+ γδ T cells in the intestinal mucosa from HCs, mildly active CD patients, and moderately active CD patients. (D) Pooled data compared the PD-1 expression on CD8+ γδ T cells in the intestinal mucosa from HCs, mildly active and moderately active CD patients. HLA-DR: activation marker, PD-1: immunosuppressive molecule. Data are mean ± SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, p < 0.0001

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BMC Immunology

ISSN: 1471-2172

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