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Fig. 3 | BMC Immunology

Fig. 3

From: Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn’s disease correlates with disease activity

Fig. 3

Enhanced cytotoxicity of intestinal CD8+ γδT cells in active CD patients was associated with disease activity degrees. (A-C) Pooled data compared the expression of cytotoxic molecules (Perforin, Granzyme B, and TRAIL) on CD8+ γδ T cells in the intestinal mucosa of HCs and active CD patients. (D-F) Pooled data compared the expression of cytotoxic molecules (Perforin, Granzyme B, and TRAIL) on CD8+ γδ T cells in the intestinal mucosa from HCs, mildly active CD patients, and moderately active CD patients. Perforin, Granzyme B, and TRAIL: cytotoxic molecules. Data are mean ± SEM. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, p < 0.0001

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BMC Immunology

ISSN: 1471-2172

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