Fig. 4

ROC curve analysis of CD8⁺ γδ T cells in active CD patients. (A) To distinguish between healthy controls and active CD cases. HLA-DR⁺ CD8⁺ γδT cell ratio (AUC, 0.886), CD8⁺ γδT ratio (AUC, 0.819), and CD8⁺ γδT count (AUC, 0.776) showed the best predictive value for active CD. (B) To distinguish between mildly active CD cases and moderately-severely active CD cases. Granzyme B⁺ CD8⁺ γδT cell ratio (AUC, 0.846) and Perforin⁺ CD8⁺ γδT cell ratio (AUC, 0.755) showed a good value to predict the moderately-severely active CD cases. AUC is an area under the curve