Table 1 Demographic characteristics of the study subjects according to regions of Ghana

Age, years, mean ± SEM (95% CI)

20 ± 2.459 (15.65–25.49)

19.40 ± 2.39 (14.62–24.18)

23.98 ± 2.558 (18.87–29.10)

19.75 ± 2.411 (14.93–24.57)

27.75 ± 2.167 (23.41–32.09)

22.85 ± 3.053 (16.74–28.96)

22.90 ± 2.424 (18.05–27.75)

21.15 ± 2.595 (15.96–26.34)

21.80 ± 3.08 (15.64–27.96)

18.27 ± 1.862 (14.54–21.99)

21.84 ± 0.799 (20.27–23.41)

Sex (Female/Male), n

60 (35/25)

60 (27/33)

60 (33/27)

60 (37/23)

60 (34/26)

60 (31/29)

60 (40/20)

60 (36/24)

60 (35/25)

60 (36/24)

600 (344/266)

Diagnosis, n/N (%)

    Microscopy +

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

300/600 (50.0)

    Microscopy -

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

30/60 (50.0)

300/600 (50.0)

    Parasite density/uL

Mean (SEM)

55,346 (13,423)

85,122

(30,345)

35,217

(11,091)

181,296

(44,939)

35,911

(9309)

178,747

(34,438)

104,809

(20,736)

229,452

(72,305)

48,254

(10,932)

47,582

(8277)

104,392

(11,508)

Antibodies, median (Range), ng/mL

    gSG6-P1

1234.0(0.0-4842.0)

1196.0(455.6-35730.0)

1394.0 (0.0-4739)

1297.0 (0.0-3364.0)

1265 (0.0-5866.0)

1117.0 (459.2–3979.0)

1125.0 (415.4–2340.0)

1953.0 (0.0-5114.0)

1001.0 (395.2–5697.0)

1049.0 (627.5–4936)

1352.0(0.0-35730.0)

    Pfs230

4799.0 (0.0-31670.0)

1891.0 (550.7–7429.0)

1932.0 (664.2–7236.0)

1550.0 (0.0-12252.0)

1392.0 (0.0-4538.0)

2506.0 (0.0-34074.0)

2392.0 (0.0-8597.0)

2392.0 (964.4-14055.0)

2267.0 (927.5-15022.0)

2630.0 (0.0-15504.0

2140.0 (0.0-34074.0)

    PfEBA175-3R

7555.0 (0.0-106964.0)

6535.0 (1899.0-77800.0)

5699.0 (860.7-53898.0)

5618.0 (860.7-216558.0)

4276.0 (0.0-38402.0)

19423.0 (0.0-8433172.0)

4712.0 (909.8-38258.0)

10417.0 (0.0-241151.0

8863.0 (0.0-335362.0)

5000.0 (0.0-247994.0)

6769.0 (0.0-8433172.0)

Hb Genotypes, n/N (%)

    AA

44/52 (84.6)

41/52(78.8)

40/53 (75.5)

51/60 (85.0)

38/43 (88.4)

44/55 (80.0)

18/26 (69.2)

43/51 (84.3)

46/54 (85.1)

33/58 (56.9)

398/504 (79.0)

    AC

2/52 (3.8)

6/52 (11.5)

4/53 (7.5)

2/60 (3.3)

1/43 (2.3)

5/55 (9.1)

4/26 (15.4)

5/51 (9.8)

3/54 (5.6)

2/58 (3.4)

34/504 (6.7)

    AF

1/52 (1.9)

-

1/53 (1.9)

1/60 (1.7)

-

-

-

-

-

1/58 (1.7)

4/504 (0.8)

    AS

5/52 (9.6)

3/52 (5.8)

7/53 (13.2)

6/60 (10.0)

4/43 (9.3)

4/55 (7.3)

1/26 (3.8)

2/51 (3.9)

4/54 (7.4)

21/58 (36.2)

57/504 (11.3)

    CC

-

-

-

-

-

2/55 (3.6)

-

1/51 (2.0)

-

-

3/504 (0.6)

    CS

-

2/52 (3.8)

1/53 (1.9)

-

-

-

-

-

-

-

3/504 (0.6)

    SS

-　

-　

-　

-　

-　

-　

-　

-　

1/54 (1.9)

-　

1/504 (0.2)

    ACF

-　

-　

-　

-　

-　

-　

3/26 (11.5)

-　

1/54 (1.9)

-　

4/504 (0.8)