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Table 2 Self-infusion training experiences of the vial and PFS cohorts in the pump subgroup

From: Subcutaneous immunoglobulin replacement therapy in patients with immunodeficiencies – impact of drug packaging and administration method on patient reported outcomes

Training characteristics (Pump)

Vial cohort (A)

PFS cohort (B)

p values

Summary

n

Summary

n

A vs. B

Number of training sessions, n (%)

1

21 (58.3%)

36

11 (30.6%)

36

0.007

2

10 (27.8%)

13 (36.1%)

3

5 (13.9%)

6 (16.7%)

4

0 (0.0%)

3 (8.3%)

5

0 (0.0%)

0 (0.0%)

>5

0 (0.0%)

3 (8.3%)

Location of training, n (%)

Doctors

1 (2.8%)

36

2 (5.6%)

36

0.57

Home

16 (44.4%)

19 (52.8%)

Hospital

16 (44.4%)

10 (27.8%)

Inf Center

2 (5.6%)

2 (5.6%)

Othera

1 (2.8%)

3 (8.3%)

Length of training session (hours)

1.3 [1.0, 2.0]

34

2.0 [1.5, 3.0]

34

0.004

Ease of learning to infuse, n (%)

Very difficult

2 (5.6%)

36

1 (2.8%)

36

0.98

Difficult

3 (8.3%)

4 (11.1%)

Neither

5 (13.9%)

4 (11.1%)

Easy

12 (33.3%)

14 (38.9%)

Very easy

14 (38.9%)

13 (36.1%)

Satisfaction with training, n (%)

Very dissatisfied

0 (0.0%)

36

0 (0.0%)

36

0.26

Dissatisfied

0 (0.0%)

1 (2.8%)

Neither

0 (0.0%)

1 (2.8%)

Satisfied

9 (25.0%)

11 (30.6%)

Very satisfied

27 (75.0%)

23 (63.9%)

Concerns during training, n (%)

Drawing drug

8 (23.5%)

34

3 (8.3%)

36

0.06

Inserting needle

12 (35.3%)

18 (50.0%)

Using pump

3 (8.8%)

0 (0.0%)

Prime tube

1 (2.9%)

5 (13.9%)

Otherb

0 (0.0%)

0 (0.0%)

No concerns

10 (29.4%)

10 (27.8%)

  1. Data were compared using Mann-Whitney test (ease of SCIg training, number of SCIg training sessions) or Fisher’s exact test (SCIg training location, type of SCIg trainer). Significant p values are in bold
  2. PFS pre-filled syringes, SCIg subcutaneous immunoglobulin
  3. aOther training locations: Institut de recherches cliniques de Montréal (vials, n=1; PFS, n=3) or a local community service center (vials, n=0; PFS, n=1)
  4. bOther concerns: applying needles to tubing (vials, n=0; PFS, n=1)