Figure 1From: Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureusTruncated CHIPS variants inhibit C5a induced cell activation. Fluo-3AM labeled U937/C5aR transfectants were preincubated with full-length CHIPS1–121, CHIPS with N-terminal truncation (CHIPS ΔN), CHIPS with C-terminal truncation (CHIPS ΔC) and CHIPS with truncations in both the N- and C-terminal ends (CHIPS ΔN/C) and stimulated with 1 nM C5a. Results are expressed as percentage inhibition of buffer treated cells and are from a representative experiment.Back to article page