Figure 1

Phenogram of ruminant immunoglobulin λ variable genes. Sequences corresponding to the V region but excluding CRD3 were aligned and phylogenetically analyzed as described in the methods. IGKV11 was used as an outgroup. Ovine genomic sequences 1.2, 1.3, 2.1, 2.2, 3, 3.1, 4.1, 4.2, 5.1, 5.2, 5.3, 5.4, 6.1, 6.2, 8.0, 9, 10, 12.1, 12.2, 16.1, 16.2, 17, 18, 26.1, 26.2, 26.3 (AF040900–AF040924, M60441) are from Reynaud et al. [13] Ovine sequences 6a, 6b, 6c and 6d (AF038145–AF038148) are derived from cDNA [14].