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Figure 3 | BMC Immunology

Figure 3

From: The expression of the β-defensins hBD-2 and hBD-3 is differentially regulated by NF-κB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis

Figure 3

PMNs enhances hBD-2 and hBD-3 expression during C. albicans infection. OE21 cells were stimulated with 0.5 × 104 C. albican/ml or 0.5 × 106 PMNs/ml alone or indicated combinations in a transwell setting for 24 h. A) hBD-2 and B) hBD-3 gene expression was assessed by real time RT-PCR. Means ± s.d. of three independent experiments performed in triplicate are shown, * indicates p-value <0,05, ** indicates synergistic effects with a p-value <0,05.

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