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Table 1 The relative frequencies of 12- and 23-cRS in VH, Vκ, and control DNA.

From: Conserved cryptic recombination signals in Vκ gene segments are cleaved in small pre-B cells

 

12-cRS

23-cRS

 

Orientation 1

Orientation 2

Orientation 1

Orientation 2

 

Potential 12-cRS

RIC12

≥ -45

Potential 12-cRS

RIC12

≥ -45

Potential 23-cRS

RIC23

≥ -65

Potential 23-cRS

RIC23

≥ -65

Vκ gene segments

3729

75

(.020)

2588

81

(.031)

3628

131

(.036)

2367

215

(.091)

VH gene segments

8647

223

(.026)

8976

299

(.033)

8312

135

(.016)

8109

302

(.037)

Ch. 8 (AC084823)

15401

259

(.017)

17480

321

(.018)

15401

701

(.046)

17478

831

(.048)

  1. RIC12 and RIC23were computed for all 28-bp and 39-bp sequences beginning with a CA-dinucleotide in both O1 and O2 in VH and Vκ gene segments, and in a 212-kb portion of chromosome 8 (accession number AC084823). The number of sequences with RIC above -45 and above -65 are shown with the relative frequencies shown in parentheses.