Selected differential spots in SL preparations of two different donors. 3D images of differentially expressed proteins in the lysosomal preparations of donor 1 and donor 2. Two proteins (#1: MHC class II alpha chain and #2: capping protein (actin filament), gelsolin-like) are reduced in donor 2 (A) and two proteins (#3: chaperonin containing TCP1, subunit 8 and #4: capping protein (actin filament), gelsolin-like) are reduced in donor 1 (B). The bold grey line indicates the same location in both images. The intensity of the spot is indicated by the 3D views. Spots #2 and #4 presumably represent isoforms of the gelsolin-like capping protein.