Degradation of IL-4 in pancreatitis-associated ascitic fluid (left) and in plasma (right). PAAF or plasma from pancreatitis were pooled and overloaded with 25 pg/ml IL-4 and the concentration was measured at different time-points. In ascitic fluid, degradation of IL-4 was observed, with a half-life of 16.4 min. By contrast, half life in plasma was 51.1 min. Values are the mean of three different experiments.