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Figure 3 | BMC Immunology

Figure 3

From: Enhancement of the priming efficacy of DNA vaccines encoding dendritic cell-targeted antigens by synergistic toll-like receptor ligands

Figure 3

In vivo CTL activity after priming with adjuvanted DNA vaccine encoding ovalbumin and adenoviral vector booster immunization. Mice (n = 3) were primed either with DEC-Ova or Con-Ova in the presence of CpI:C and boosted with the Ad-Ova vector. One week after the boost, mice received a 1 to 1 mixture of SIINFEKL peptide-loaded and non-loaded syngenic donor splenocytes also differing in the intensity of the CFSE-labelling. One day after immunization, the percentage of SIINFEKL loaded donor cells (A) and tetramer + CD8+ cells (B) was determined. The levels of significance in the Bonferroni Multiple Comparison test are indicated (* p < 0.05; ** p < 0.01; ***p < 0.001).

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BMC Immunology

ISSN: 1471-2172

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