Figure 2

Kinetics of Tissue Localization following Adoptive Transfer of T-lux T cells. The kinetics of naïve T cell homing were assessed following adoptive transfer of 1 × 10⁷ T-lux CD3⁺ cells into CD45.1-positive, C57BL/6 recipients (N = 8). Recipient mice were imaged for whole body bioluminescence at timed intervals following transfer. (A) Representative images from a single mouse for each of the indicated time points. Additional reference anatomical map shown below 24-hour time point. Pseudocolor scales are shown to right of figures. The mean bioluminescent signal of the cohort for each time point is displayed in (B). Control bioluminescence from mice receiving non-transgenic T cells ('non-lux' T cells) is also shown. Error bars indicate SEM.