Table 1 Surface phenotype of cytokine-differentiated and freshly isolated NK cells.
Cell surface antigen | UCB MNC | PB MNC | CD34+-derived NK cells (15+21) | CD34-lineage- derived NK cells (IL-15) | CD34-lineage- derived NK cells (15+21) |
|---|---|---|---|---|---|
CD56+ | 23 ± 5 | 35.4 ± 9 | 22.9 ± 5 | 94 ± 2 | 92 ± 2 |
CD56+16+ | 14.5 ± 7 | 29.5 ± 5 | 6.5 ± 2 | 4 ± 1 | 0.6 ± 0.2 |
CD56+94+ | 20.9 ± 4 | 26.7 ± 7 | 17.6 ± 4 | 47.5 ± 8 | 52 ± 5 |
CD56+NKp46+ | 22.3 ± 5 | 28.6 ± 4 | 21.1 ± 4 | 65.5 ± 8 | 91.5 ± 1 |
CD56+NKG2D+ | 15.4 ± 2 | 31.4 ± 9 | 5.0 ± 0.8 | 16.5 ± 4 | 68.5 ± 5 |
CD56+158a+ | 4.6 ± 1 | 4.5 ± 1.5 | 0.6 ± 0.5 | 0.01 ± 0.01 | 0.5 ± 0.2 |
CD56+158b+ | 5.9 ± 1 | 11.5 ± 6 | 1.2 ± 1 | 0.1 ± 0.1 | 1.8 ± 0.5 |
CD56+161+ | 23.3 ± 6 | 32.2 ± 7 | 1.5 ± 0.5 | 8.3 ± 2 | 2.1 ± 0.5 |
CD56+244+ | 16.9 ± 6 | 30.8 ± 4 | 19.8 ± 5 | 89.6 ± 5 | 81.7 ± 2 |
IL-21R+ | 3.6 ± 0.9 | 2.2 ± 1 | 12.9 ± 6 | 94.2 ± 2 | 76.5 ± 3 |