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Figure 3 | BMC Immunology

Figure 3

From: Understanding diversity of human innate immunity receptors: analysis of surface features of leucine-rich repeat domains in NLRs and TLRs

Figure 3

An example of mapping the RI amino acid sequence into structure and of RI surface partitioning. A, Mapping between an LRR sequence motif and the RI structure. RI sequence was searched for the conserved LRR pattern LaaLXL, and 16 LRRs were identified. The residue X (magenta) was then used as a reference to define residues belonging to the inner concave surface (yellow and magenta), N-terminal side (green), C-terminal side (blue), and outer convex surface (red). Mapping between a general LRR motif sequence and the structure of LRR #13 is shown by coloring. B, Full RI surface partitioned into four parts as described above.

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