Figure 3

Multiple Vγ2 nucleotypes comprise individual public clonotypes. Public clonotypes are usually encoded by more than one circulating nucleotype. The amino acid sequences appear in the vertical box at the left. The possible nucleotypes that encode this clonotype are shown in the horizontal boxes as nucleotide sequences; the hypervariable or N nucleotides are shown in bold type. The histograms show the abundance of each nucleotype (as a proportion of all sequences in the CD56+ or CD56- samples) among IPP-expanded cell lines generated from PBMC collected in 2007 or 2008. The bar height represents the total nucleotype abundance; the dark shaded portion indicates the fraction of sequences in the CD56+ subset and the light shaded region shows the fraction of nucleotypes in the CD56- subset. The label "ND" indicates that nucleotype was "not detected" in the 2007 or 2008 cell lines.