Migratory activity of CD8+ T lymphocytes. Each graph shows on the left side the time-course of the mean migratory activity and on the right side the time-average of the migratory activity as mean value and standard deviation of the same experiments. In (A), nine experiments were performed with activated and naive CD8+ T lymphocytes, in (B) four experiments were performed with naïve CD8+ T lymphocytes (1 μM dopamine). For each experiment, blood from different donors was used. Asterisks mark statistically significant changes (p < 0.05). (C) Shows the western blot analysis of the neurotransmitter receptors expressed on naïve and activated CD8+ T lymphocytes. β-Actin served as loading control.