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Figure 2 | BMC Immunology

Figure 2

From: Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarization

Figure 2

MAPK activation in DCs. Representative histograms of (A) ERK and (B) p38 phosphorylation in DCs 20 minutes after stimulation. C-E. Ratios of p-ERK/p-p38 (C), phosphorylation of ERK (D) and p38 (E) 20 minutes after stimulation in the presence of LPS. Expression induced by LPS (MFI of 49 ± 12 for p-ERK and 16 ± 9 for p-p38) was set to 100% (dashed line). Relative expression levels or ratios are shown. * P < 0.05 compared to LPS stimulation. F and G. Correlation of p-ERK/p-p38 ratio and IL-4 (F) or IFN-γ (G) production by T-cells. All data are relative to stimulation with LPS only and combined results from 4 independent experiments are shown.

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BMC Immunology

ISSN: 1471-2172

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