Table 1 Splenocyte subpopulations in AUF1+/+, AUF1-/- and chimeric mice.
From: AUF1 is involved in splenic follicular B cell maintenance
|  | AUF1+/+ (n= 10) | AUF1-/- (n= 10) | WT→RAG1-/- (n= 4) | KO→RAG1-/- (n= 4) | WT→KO (n= 4) | KO→WT (n= 4) |
|---|---|---|---|---|---|---|
Total splenocytes | 70.8 ± 10.7 | 41.6 ± 7.6 | 34.8 ± 3.6 | 24.7 ± 3.8 | 47.3 ± 4.1 | 73.6 ± 7.9 |
B220+ | 37.5 ± 3.3 | 23.4 ± 1.5 | 16.6 ± 0.9 | 10.6 ± 1.4 | 24.3 ± 6.2 | 39.7 ± 4.3 |
   IgMlo, IgDhi (FO) | 26.0 ± 2.3 (69.3) | 13.1 ± 0.8 (55.3) | 11.6 ± 0.1 (69.6) | 5.3 ± 0.7 (50.0) | 16.7 ± 0.6 (68.8) | 21.0 ± 1.7 (53.0) |
   IgMhi, IgDhi (T2) | 4.6 ± 0.9 (12.3) | 4.3 ± 0.5 (18.2) | 1.5 ± 0.3 (9.3) | 1.6 ± 0.5 (14.6) | 3.1 ± 0.9 (12.8) | 8.2 ± 0.2 (20.7) |
   IgMhi, IgDlo (T1) | 3.1 ± 0.5 (8.3) | 2.4 ± 0.3 (9.8) | 0.9 ± 0.2 (5.2) | 1.1 ± 0.1 (10.5) | 1.3 ± 0.1 (5.2) | 3.9 ± 1.1 (9.9) |
   CD21hiCD23lo (MZB) | 3.6 ± 0.6 (9.6) | 4.3 ± 0.5 (18.4) | 2.2 ± 0.2 (13.2) | 2.7 ± 0.3 (25.7) | 1.6 ± 0.4 (6.6) | 5.2 ± 1.2 (13.1) |
   CD21intCD23hi (FO) | 29.8 ± 0.8 (79.5) | 13.2 ± 2.7 (59.1) | 11.6 ± 1.9 (70.0) | 5.5 ± 0.9 (52.0) | 20.6 ± 0.2 (84.9) | 23.9 ± 1.3 (60.2) |
   CD21loCD23lo (NF) | 3.4 ± 0.7 (9.1) | 3.9 ± 2.6 (17.5) | 2.5 ± 0.2 (15.1) | 2.2 ± 0.9 (20.5) | 1.9 ± 0.5 (7.8) | 10.0 ± 0.1 (25.3) |
   IgMhiIgDloCD21lo (NF) | 2.0 ± 0.3 (5.2) | 2.3 ± 0.3 (8.0) | ND | ND | ND | ND |
   IgMhiIgDhiCD21int (FOII) | 3.4 ± 0.6 (9.1) | 3.6 ± 0.8 (13.1) | ND | ND | ND | ND |
   IgMloIgDhiCD21int (FO) | 24.3 ± 2.4 (66.0) | 14.6 ± 2.0 (53.0) | ND | ND | ND | ND |
   IgMhiIgDhiCD21hi (MZP) | 1.7 ± 0.4 (4.5) | 1.5 ± 0.3 (5.5) | ND | ND | ND | ND |
   IgMhiIgDloCD21hi (MZ) | 4.4 ± 0.8 (11.2) | 4.7 ± 0.5 (16.2) | ND | ND | ND | ND |
CD3+ F4/80+ | 21.3 ± 1.4 0.9 ± 0.1 | 13.8 ± 0.6 0.9 ± 0.1 | 15.0 ± 0.7 2.1 ± 1.4 | 10.4 ± 0.5 3.0 ± 0.7 | 15.8 ± 1.2 1.1 ± 0.3 | 23.6 ± 3.3 1.0 ± 0.2 |
CD94+CD3- | 1.0 ± 0.3 | 1.0 ± 0.1 | ND | ND | ND | ND |
CD16/CD32+B220- | 4.3 ± 1.3 | 4.4 ± 1.1 | ND | ND | ND | ND |